INTERRELATIONS OF PLASMA POTASSIUM CONCENTRATION, PLASMA SODIUM CONCENTRATION, ARTERIAL pH AND TOTAL EXCHANGEABLE POTASSIUM*

Are the total exchangeable sodium, total exchangeable potassium and total body water the only determinants of the plasma water sodium concentration?

The dysnatraemias are common electrolyte disorders encountered in hospitalized patients [1]. The pathophysiology and approach to management of these electrolyte disorders have been well characterized. It is well known that the total exchangeable sodium (Nae), total exchangeable potassium (Ke) and total body water (TBW) are the major determinants of the plasma water sodium concentration ([Na]pw)...

Interrelations between total exchangeable sodium, potassium, body water, and serum sodium and potassium concentrations in hyponatremic and normonatremic heart disease.

Relation of arterial pressure with exchangeable and total body sodium and with plasma exchangeable and total body potassium in essential hypertension.

C. B E R E T T A P I C C O L I , D . L. DAVIES,* K . B O D D Y , ? J . J . B R O W N , A. M. M. C U M M I N G , W. B. E A S T , ? R . F R A S E R , A . F. L E V E R , P . P A D F I E L D , * J . I . S. R O B E R T S O N , P. W E I D M A N N S A N D E. D . W I L L I A M S ? MR C Blood Pressure Unit and 'Department of Medicine, Western Injrmary, Glasgow, t Scottish Universities Research and React...

Insulinotropic effect of high potassium concentration beyond plasma membrane depolarization.

The question whether K⁺ depolarization is an appropriate experimental substitute for the physiological nutrient-induced depolarization of the β-cell plasma membrane was investigated using primary mouse β-cells and islets. At basal glucose 40 mM K⁺ induced a massive monophasic response, whereas 15 mM K⁺ had only a minimal insulinotropic effect, even though the increase in the cytosolic Ca²⁺ conc...

A system for automatic feedback control of plasma potassium concentration.

A system is described for automatic feedback control of plasma potassium concentration in experimental animals. Plasma potassium was monitored continuously and the signal compared with the desired plasma potassium concentration. The resulting error signal controlled the infusion rates of a concentrated potassium chloride solution (50 or 200 mmol litre-1) and a solution of 50% glucose with insul...